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Publicaciones científicas

2023

D-galactose Supplementation for the Treatment of Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE): A Pilot Trial of Precision Medicine After
Epilepsy Surgery.

Neurotherapeutics. 2023 Jun 6. doi: 10.1007/s13311-023-01395-z.

Aledo-Serrano Á, Valls-Carbó A, Fenger CD, Groeppel G, Hartlieb T, Pascual I, Herraez E, Cabal B, García-Morales I, Toledano R, Budke M, Beltran-Corbellini Á, Baldassari S, Coras R, Kobow K, Herrera DM, Del Barrio A, Dahl HA, Del Pino I, Baulac S, Blumcke I, Møller RS, Gil-Nagel A.

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

Nat Commun. 2023 May 15;14(1):2779. doi: 10.1038/s41467-023-38410-y.

Costa-Machado LF, Garcia-Dominguez E, McIntyre RL, Lopez-Aceituno JL, Ballesteros-Gonzalez Á, Tapia-Gonzalez A, Fabregat-Safont D, Eisenberg T, Gomez J, Plaza A, Sierra-Ramirez A, Perez M, Villanueva-Bermejo D, Fornari T, Loza MI, Herradon G, Hofer SJ, Magnes C, Madeo F, Duerr JS, Pozo OJ, Galindo MI, Del Pino I, Houtkooper RH, Megias D, Viña J, Gomez-Cabrera MC, Fernandez-Marcos PJ.

Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder

Frontiers in Cell and Developmental Biology 2023 Feb 1;11:1112062. doi: 10.3389/fcell.2023.1112062.

Ahmed NY, Knowles R, Liu L, Yan Y, Li X, Schumann U, Wang Y, Sontani Y, Reynolds N, Natoli R, Wen J, Del Pino I, Mi D, Dehorter N.

2021

Developmental disruption of Erbb4 in Pet1+ neurons impairs serotonergic sub-system connectivity and memory formation

Front Cell Dev Biol. 2021 Dec 10;9:770458. doi: 10.3389/fcell.2021.770458.

Candela Barettino*, Alvaro Ballesteros-González*, Andrés Aylón, Xavier Soler, Leticia Ortí, Selene Díaz, Isabel Reillo, Francisco G. García, Francisco J. Iborra, Cary Lai, Nathalie Dehorter, Xavier Leinekugel, Nuria Flames and Isabel Del Pino.

* co-first authors

Sodium channel blockers for the treatment of epilepsy in CDKL5 deficiency disorder: Findings from a multicenter cohort

Epilepsy Behav. 2021 May;118:107946. doi: 10.1016/j.yebeh.2021.107946.

Aledo-Serrano Á, Gómez-Iglesias P, Toledano R, Garcia-Peñas JJ, Garcia-Morales I, Anciones C, Soto-Insuga V, Benke TA, Del Pino I, Gil-Nagel A.

2017

Abnormal wiring of CCK+ basket cells disrupts spatial information coding

Nat Neurosci. 2017 Jun;20(6):784-792. doi: 10.1038/nn.4544. Epub 2017 Apr 10.

Del Pino I, Brotons-Mas JR, Marques-Smith A, Marighetto A, Frick A, Marín O, Rico B.

2015

Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch

Science. 2015 Sep 11;349(6253):1216-20. doi: 10.1126/science.aab3415.

Dehorter N, Ciceri G, Bartolini G, Lim L, Del Pino I, Marín O.

2014

Sculpting circuits: CRH interneurons modulate neuronal integration

Dev Cell. 2014 Sep 29;30(6):639-40. doi: 10.1016/j.devcel.2014.09.006.

​Del Pino I, Marín O.

Proteomic analysis of glycine receptor β subunit (GlyRβ)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors

J Biol Chem. 2014 Apr 18;289(16):11396-409. doi: 10.1074/jbc.M113.504860. Epub 2014 Feb 7.

Del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I.

2013

Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes

Neuron. 2013 Sep 18;79(6):1152-68. doi: 10.1016/j.neuron.2013.07.010.

Del Pino I, García-Frigola C, Dehorter N, Brotons-Mas JR, Alvarez-Salvado E, Martínez de Lagrán M, Ciceri G, Gabaldón MV, Moratal D, Dierssen M, Canals S, Marín O, Rico B.

2012

Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth

Development. 2012 Sep;139(17):3200-10. doi: 10.1242/dev.080564.

Chacón MR, Navarro AI, Cuesto G, Del Pino I, Scott R, Morales M, Rico B.

2011

The trafficking proteins Vacuolar Protein Sorting 35 and Neurobeachin interact with the glycine receptor β-subunit

Biochem Biophys Res Commun. 2011 Sep 2;412(3):435-40. doi: 10.1016/j.bbrc.2011.07.110. Epub 2011 Jul 29.

Del Pino I, Paarmann I, Karas M, Kilimann MW, Betz H.

2010

Neuroblastoma phox2b variants stimulate proliferation and dedifferentiation of immature sympathetic neurons

J Neurosci. 2010 Jan 20;30(3):905-15. doi: 10.1523/JNEUROSCI.5368-09.2010.

​Reiff T, Tsarovina K, Majdazari A, Schmidt M, del Pino I, Rohrer H.

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